General impact 16

Prime assembly with linear DNA donors enables large genomic insertions

Prime assembly with linear DNA donors enables large genomic insertions Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10460-4 Prime assembly can initiate Gibson-like assembly in cells to generate gene i…

Why it matters

A useful signal for anyone monitoring prime. The assembly factor makes this more consequential than it first appears.

Read full article at Nature →

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