General
impact 16
Molecular basis for methylation-sensitive editing by Cas9
Molecular basis for methylation-sensitive editing by Cas9 Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10384-z ThermoCas9, a genome-editing enzyme that is sensitive to the DNA methylation status of thβ¦
Why it matters
A useful signal for anyone monitoring basis. The molecular factor makes this more consequential than it first appears.